Leveraging Similar Regions to Improve Genome Data Processing
نویسندگان
چکیده
Leveraging Similar Regions to Improve Genome Data Processing
منابع مشابه
SiRen: Leveraging Similar Regions for Efficient & Accurate Variant Calling
Next-generation genomic sequencing costs are rapidly decreasing, having recently reached the $1000per-genome barrier, a likely tipping point for widespread clinical use. However, genomic analysis techniques have failed to keep pace. In particular, the process of variant calling, or inferring a sample genome from the noisy sequencing data, introduces major computational and statistical challenge...
متن کاملImproved methods for multi-trait fine mapping of pleiotropic risk loci
MOTIVATION Genome-wide association studies (GWAS) have identified thousands of regions in the genome that contain genetic variants that increase risk for complex traits and diseases. However, the variants uncovered in GWAS are typically not biologically causal, but rather, correlated to the true causal variant through linkage disequilibrium (LD). To discern the true causal variant(s), a variety...
متن کاملIdentification of bovine, ovine and caprine pure and binary mixtures of raw and heat processed meats using species specific size markers targeting mitochondrial genome
A specific polymerase chain reaction (PCR) method was applied for identification of bovine (Bos taurus), ovine (Ovis aries) and caprine (Capra hircus) pure and binary mixtures of raw and heat-processed meats. These meats are used in food industry products and/or for direct consumption of consumers. The mitochondrial DNA was amplified as a template in a PCR reaction by use of specific primers re...
متن کاملMLIFT: Enhancing Multi-label Classifier with Ensemble Feature Selection
Multi-label classification has gained significant attention during recent years, due to the increasing number of modern applications associated with multi-label data. Despite its short life, different approaches have been presented to solve the task of multi-label classification. LIFT is a multi-label classifier which utilizes a new strategy to multi-label learning by leveraging label-specific ...
متن کاملMolecular Comparison of Three Different Regions of the Genome of Infectious Bronchitis Virus Field Isolates and Vaccine Strains
Rapid detection and differentiation of infectious bronchitis virus (IBV) involved in the disease outbreak is very important for controlling disease and developing new vaccines. In the present study, three regions of the genome of IBV vaccine and field isolates including S1 gene, gene 3 and nucleocapsid (N) gene along with 3' untranslated region (3' UTR) were amplified and subjected to restricti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2015